Validity of a New Respiratory Resistance Measurement Device to Detect Glottal Area Change
Validity of a New Respiratory Resistance Measurement Device to Detect Glottal Area Change
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DOI：
10.1016/j.jvoice.2013.01.006
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发表时间：
2013-05-01
期刊：
影响因子：
2.2
通讯作者：
Solomon, Nancy Pearl
中科院分区：
文献类型：
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作者：
Gallena, Sally J. K.;Tian, Wei;Solomon, Nancy Pearl
Objective.旨在确定使用气流扰动装置（APD）测量的呼吸阻力（R-r）值与假装反常声带运动（PVFM）（也称为声带功能障碍）时声门区（GA）喉镜图像之间的相关性。在R-r和GA之间存在强的反比关系，使得喉部收缩可以通过APD测量的R-r来检测和定量。前瞻性、单一受试者研究。一个健康的成年人假装呼吸，这是PVFM的特征。同时记录R-r和GA，同步，并分析三个完整的呼吸周期，在吸气过程中发生显著的声门收缩。交叉相关分析显示，在PVFM假呼吸过程中，GA与R-r之间存在较强的负相关（-0.824），GA降低时R-r增加。APD测量的R-r似乎是一种可行的非侵入性方法，用于诊断筛查和监测PVFM相关呼吸困难患者的治疗结局。
Objective. To determine the correlation between respiratory resistance (R-r) values measured with the Airflow Perturbation Device (APD) to laryngoscopic images of glottal area (GA) in feigned paradoxical vocal fold motion (PVFM), also known as vocal cord dysfunction.Hypothesis. There is a strong inverse relationship between R-r and GA such that laryngeal constriction can be detected and quantified by APD-measured R-r.Study Design. Prospective, single subject study.Methods. A healthy adult feigned breathing that was characteristic of PVFM. R-r and GA were simultaneously recorded, synchronized, and analyzed for three complete breathing cycles with significant glottal constriction occurring during inspiration.Results. Cross-correlation analysis revealed a strong negative correlation (-0.824) between GA and R-r during feigned PVFM breathing such that R-r increased when GA decreased.Conclusion. APD-measured R-r appears to be a viable noninvasive method for diagnostic screening and monitoring of treatment outcomes for individuals presenting with dyspnea related to PVFM.