Preparation, structure, and in vitro chemical durability of yttrium phosphate microspheres for intra-arterial radiotherapy.
Preparation, structure, and in vitro chemical durability of yttrium phosphate microspheres for intra-arterial radiotherapy.
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动脉内放射治疗用磷酸钇微球的制备、结构和体外化学耐久性。
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
H. Kanetaka
中科院分区：
文献类型：
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作者：
M. Kawashita;N. Matsui;Zhixia Li;T. Miyazaki;H. Kanetaka
含有钇和/或磷的化学耐久性微球可用于动脉内放射治疗。在本研究中，我们尝试制备具有高化学耐久性的磷酸钇（YPO₄）微球。将含有钇和磷酸盐离子的明胶液滴在油包水乳液中冷却固化，然后在1100℃下进行热处理，成功获得了表面光滑、直径约为25μm的YPO4微球。经过热处理的微球在 pH = 6 和 7 的模拟体液中的化学耐久性足够高，足以用于动脉内放射治疗的临床应用。
Chemically durable microspheres containing yttrium and/or phosphorus are useful for intra-arterial radiotherapy. In this study, we attempted to prepare yttrium phosphate (YPO₄) microspheres with high chemical durability. YPO₄ microspheres with smooth surfaces and diameters of around 25 μm were successfully obtained when gelatin droplets containing yttrium and phosphate ions were cooled and solidified in a water-in-oil emulsion and then heat-treated at 1100°C. The chemical durability of the heat-treated microspheres in a simulated body fluid at pH = 6 and 7 was high enough for clinical application of intra-arterial radiotherapy.
RIF-1 肿瘤中肿瘤 pH 值和细胞对热敏感性的比较。
影响因子：
11.2
作者：
Hiraoka,M;Hahn,GM
通讯作者：
Hahn,GM