HIV and Bone Complications: Understudied Populations and New Management Strategies
HIV and Bone Complications: Understudied Populations and New Management Strategies
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DOI：
10.1007/s11904-016-0341-9
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发表时间：
2016-12-01
影响因子：
4.6
通讯作者：
Brown, Todd T.
中科院分区：
文献类型：
--
作者：
Yin, Michael T.;Brown, Todd T.
人们已经充分认识到，与艾滋病毒感染和某些抗逆转录病毒药物有关的骨质疏松症和骨折的风险较高，而且越来越认识到需要对老年人进行风险分层。本次审查的重点是新出现的数据与艾滋病毒/丙型肝炎病毒合并感染的骨并发症，在儿童和青少年，与暴露前预防（PrEP），以及新的管理策略，以尽量减少对骨骼的负面影响的艺术。
The higher risk of osteoporosis and fracture associated with HIV infection and certain antiretrovirals has been well established and the need for risk stratification among older adults increasingly recognized. This review focuses upon emerging data on bone complications with HIV/HCV coinfection, in children and adolescents, and with pre-exposure prophylaxis (PrEP), as well as new management strategies to minimize the negative effects of ART on bone.