Fertility treatments, maternal intelligence, and child cognition.
Fertility treatments, maternal intelligence, and child cognition.
复制标题
生育治疗、母亲智力和儿童认知。
DOI：
10.1111/1471-0528.12928
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Jacobson,SW
中科院分区：
文献类型：
--
作者：
Carter,RC;Jacobson,JL;Jacobson,SW
More than three decades of research and clinical experience with fertility treatments have led to an ever-growing number of children conceived using these technologies, but recent advances in embryology and epigenetics have raised concerns regarding possible disruption to embryologic development. Although fertility treatments are associated with increased perinatal morbidity risks, most studies examining cognitive outcomes have found no differences between children conceived with fertility treatments and those spontaneously conceived (Bay et al.), Fertil Steril 2013; 100 (3): 844–53). However, previous studies have not considered important potentially confounding parental factors. Access to fertility treatments has been associated with higher parental intelligence, education, age, and socioeconomic status, which are associated with more optimal offspring cognitive development, while subfertility may be related to heritable issues associated with poorer cognitive outcomes.In this prospective study examining potential effects of fertility treatments on 5-year cognitive function, the authors addressed these confounding issues by separately examining children born to subfertile parents (time to pregnancy> 12 months) and those conceived with fertility treatments, compared with spontaneously conceived controls, and by adjusting for
