Elective cholecystectomy for the patient with sickle cell disease and asymptomatic cholelithiasis.

Elective cholecystectomy for the patient with sickle cell disease and asymptomatic cholelithiasis.
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镰状细胞病和无症状胆石症患者的选择性胆囊切除术。

DOI:
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发表时间:
1986
期刊:
The American surgeon
影响因子:
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通讯作者:
H. Reines
H. Reines
中科院分区:
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文献类型:
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作者:
W. Rambo;H. Reines

文献摘要

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本文回顾了1977-1984年10例镰状细胞病和1例镰状地中海贫血病人的择期胆囊切除术经验。与我们机构的早期回顾相比,本系列的发病率较低。这种改善归因于仔细的围手术期护理,特别是术前输血,水合和氧合。由于镰状细胞病患者寿命的延长,由于无症状胆石症的最终严重并发症的发生率,以及为了通过消除急性胆囊炎和镰状细胞肝胆危象之间的诊断混淆来简化医疗管理,作者认为,对无症状胆石症的镰状细胞病患者推荐选择性胆囊切除术。
Experience with elective cholecystectomy in ten patients with sickle cell disease and one patient with sickle-thalassemia from 1977-1984 was reviewed. In contrast to an earlier review from our institution, the current series had a low morbidity. This improvement is attributed to careful perioperative care, especially preoperative transfusion, hydration, and oxygenation. Because of the increasing longevity of sickle cell patients, because of the incidence of eventual significant complications of even asymptomatic cholelithiasis, and in order to simplify medical management by eliminating the diagnostic confusion between acute cholecystitis and sickle cell hepatobiliary crisis, the authors believe that elective cholecystectomy is to be recommended for the sickle cell patient with asymptomatic gall stones.