Depression and panic attacks: the significance of overlap as reflected in follow-up and family study data.
Depression and panic attacks: the significance of overlap as reflected in follow-up and family study data.
复制标题
抑郁症和恐慌症：随访和家庭研究数据所反映的重叠的重要性。
DOI：
10.1176/ajp.145.3.293
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Winokur,G
中科院分区：
文献类型：
--
作者：
Coryell,W;Endicott,J;Andreasen,NC;Keller,MB;Clayton,PJ;Hirschfeld,RM;Scheftner,WA;Winokur,G
方法 患有严重情感障碍的患者在入院后不久或在五个参与的三级护理中心中的任何一个首次门诊预约后的两个月内被邀请参加合作研究。纳入标准规定，所有受试者均年满 17 岁、白人、讲英语、了解亲生父母，且无任何脑部综合症、末期疾病或精神缺陷（智商低于 70）。经过系统培训的评估者使用医疗记录和完整的情感障碍和精神分裂症 (SADS) (SADS) 表 (4) 来评估基线精神病理学并得出 RDC 诊断。然后，这些评估者以 6 个月的间隔重新联系每位患者，并使用纵向间隔随访评估 (LIFE)(S) 绘制随后的症状过程，并量化其对心理社会功能的影响。
METHODPatients with major affective disorders were invited to participate in the collaborative study shortly after admission to the hospital or within 2 months of their first outpatient appointment at any of the five participating tertiary care centers. The inclusion criteria specified that all subjects be 17 years of age or older, Caucasian, English-speaking, knowledgeable about both biological parents, and free of any brain syndrome, terminal illness, or mental deficiency(IQ less than 70).Systematically trained raters used medical records and the full Schedule for Affective Disorders and Schizophrenia(SADS)(4) to assess baseline psychopathology and to reach an RDC diagnosis. These same raters then recontacted each patient at 6-month inter-vals and, using the Longitudinal Interval Follow-Up Evaluation(LIFE)(S), charted the subsequent course of symptoms and quantified their impact on psychosocial functioning.