Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43.
Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43.
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DOI：
10.1107/s1600536812043000
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发表时间：
2012-11-01
期刊：
影响因子：
--
通讯作者：
Cheng YQ
中科院分区：
文献类型：
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作者：
Liu XY;Wang C;Cheng YQ
标题化合物[系统名：（3S，8aS）-3-异丙基-六氢-吡咯并[1，2-a]吡嗪-1，4-二酮]，C10 H16 N2 O2，是从Burkholderia thailandensis MSMB 43中分离得到的一个新的环状二肽。不对称单元中有两个独立的分子。其中一个分子的五元环中的两个C原子和它们所连接的H原子以0.715（5）：0.285（5）的比例在两组位置上无序排列。 两个独立的分子具有相同的构型，根据反常色散的观察确定了手性中心的绝对构型。在晶体中，两种类型的N-H-O氢键连接独立的分子对。
The title compound [systematic name: (3S,8aS)-3-isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione], C10H16N2O2,, is a newly isolated cyclic dipeptide from Burkholderia thailandensis MSMB43. There are two independent molecules in the asymmetric unit. Two C atoms and their attached H atoms in the five-membered ring of one of the molecules are disordered over two sets of sites in a 0.715 (5):0.285 (5) ratio. The two independent molecules have the same configuration and the absolute configurations of the chiral centers were determined based on the observation of anomalous dispersion. In the crystal, two types of N—H⋯O hydrogen bonds link pairs of independent molecules.