Recombinant erythropoietin in urine - An artificial hormone taken to boost athletic performance can now be detected.

Recombinant erythropoietin in urine - An artificial hormone taken to boost athletic performance can now be detected.
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DOI:
10.1038/35015164
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发表时间:
2000-06-08
期刊:
影响因子:
64.8
通讯作者:
de Ceaurriz, J
de Ceaurriz, J
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Lasne, F;de Ceaurriz, J

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促红细胞生成素是一种刺激新红细胞生成(红细胞生成)的激素。尽管运动员非法使用重组人促红细胞生成素来促进向组织输送氧气并提高其在耐力运动中的表现,但如果没有可靠的分析程序进行监测,这种广泛使用的兴奋剂做法就无法得到控制。在这里,我们描述了一种在最近给药后检测尿液中这种药物的新技术。
Erythropoietin is a hormone that stimulates the production of new red blood cells (erythropoiesis). Although athletes use recombinant human erythropoietin illicitly to boost the delivery of oxygen to the tissues and enhance their performance in endurance sports, this widespread doping practice cannot be controlled in the absence of a reliable analytical procedure to monitor it. Here we describe a new technique for detecting this drug in urine following its recent administration.