Efficacy and safety of inhaled ciclesonide compared with chlorofluorocarbon beclomethasone dipropionate in adults with moderate to severe persistent asthma *
Efficacy and safety of inhaled ciclesonide compared with chlorofluorocarbon beclomethasone dipropionate in adults with moderate to severe persistent asthma *
复制标题
吸入环索奈德与氯氟碳二丙酸倍氯米松治疗成人中度至重度持续性哮喘的疗效和安全性*
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
T. Miyamoto
中科院分区：
文献类型：
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作者：
M. Adachi;K. Ishihara;H. Inoue;K. Kudo;Kiyoshi Takahashi;Y. Morita;Ken‐ichi Masuda;Tomoki Sakai;R. Kato;T. Miyamoto
背景和目的：吸入性皮质类固醇被认为是哮喘管理的一线治疗;然而，其使用可能受到全身和局部副作用的限制。 环索奈德是一种新型前药吸入性皮质类固醇，在肺部被激活，预计全身和局部副作用较少。本研究评价了环索奈德氢氟烷（HFA）与二丙酸倍氯米松（BDP）氯氟烃（CFC）制剂在中重度哮喘成人患者中的疗效和安全性。
Background and objective: Inhaled corticosteroids are recognized as first‐line therapy in the management of asthma; however, their use may be limited by systemic and local side‐effects. Ciclesonide, a novel pro‐drug inhaled corticosteroid, is activated in the lungs and is expected to have less systemic and local side‐effects. This study evaluated the efficacy and safety of ciclesonide in hydrofluoroalkane (HFA) compared with beclomethasone dipropionate (BDP) in a chlorofluorocarbon (CFC) formulation in adult patients with moderate to severe asthma.
影响因子：
158.5
作者：
Israel, E;Banerjee, TR;LeBoff, MS
通讯作者：
LeBoff, MS