Simple Chiral Chain Dienes as Ligands for Rh(I)-Catalyzed Conjugated Additions
Simple Chiral Chain Dienes as Ligands for Rh(I)-Catalyzed Conjugated Additions
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简单手性链二烯作为 Rh(I) 催化共轭加成的配体
DOI：
10.1021/ol901949n
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发表时间：
2009-10-15
期刊：
影响因子：
5.2
通讯作者：
Du, Haifeng
中科院分区：
文献类型：
--
作者：
Hu, Xichao;Zhuang, Minyang;Du, Haifeng
本文报道了一种简单易得的链状(3R，4R)-六-1，5-二烯-3，4-二醇(L1)作为一种新型的Rh(I)催化不对称共轭加成反应的导向配体。获得了令人振奋的产率和ee‘s，为今后手性双烯配体的设计提供了一个新的实用方向。
This paper describes that a simple and readily available chain diene (3R,4R)-hexa-1,5-diene-3,4-diol (L1) was successfully utilized as a novel steering ligand for Rh(I)-catalyzed asymmetric conjugated additions. Encouraging yields and ee's have been achieved, which may provide a new and practical direction for designing chiral diene ligands In the future.