Acute encephalopathy due to thiamine deficiency (Wernicke's encephalopathy) in a chronic hemodialyzed patient: a case report.
Acute encephalopathy due to thiamine deficiency (Wernicke's encephalopathy) in a chronic hemodialyzed patient: a case report.
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慢性血液透析患者因硫胺素缺乏所致的急性脑病（韦尼克脑病）：病例报告。
作者：
E. Descombes;C.;G. Fellay
我们报告了一名接受慢性血液透析的晚期肾病患者的病例，经红细胞转酮醇酶测定证实，该患者出现急性硫胺素缺乏症。患者出现精神错乱和严重的记忆障碍，但不存在韦尼克脑病的其他典型特征。硫胺素治疗后，几乎所有中枢神经系统症状都迅速消失。因此，对于出现中枢神经系统紊乱的慢性透析患者，即使不存在韦尼克脑病的所有典型特征，也必须考虑硫胺素缺乏的可能性。
We report the case of a patient with terminal renal disease on chronic hemodialysis who developed acute thiamine deficiency as confirmed by erythrocyte transketolase determinations. The patient presented with a confusional state and severe memory disturbances, but other classical features of Wernicke's encephalopathy were absent. Almost all central nervous system symptoms rapidly disappeared after thiamine therapy. Therefore the possibility of thiamine deficiency must be considered in patients on chronic dialysis who present with central nervous system disturbances, even if all of the classical features of Wernicke's encephalopathy are not present.