Optimisation of T2*-weighted MRI for the detection of small veins in multiple sclerosis at 3 T and 7 T
Optimisation of T2*-weighted MRI for the detection of small veins in multiple sclerosis at 3 T and 7 T
复制标题
DOI：
10.1016/j.ejrad.2011.09.023
复制
发表时间：
2013-05-01
影响因子：
3.3
通讯作者：
Morris, Peter Gordon
中科院分区：
文献类型：
--
作者：
Dixon, Jennifer Elizabeth;Simpson, Ashley;Morris, Peter Gordon
最近在7 T处的T-2*加权磁共振成像显示，通过是否存在可检测到的中央血管，可以区分白质多发性硬化症病变和无症状白质病变。目前工作的目的是通过提高对3 T和7 T静脉的灵敏度来改进技术，并评估超高场成像的好处。信噪比（SNR）测量和模拟用于比较T-2*等加权图像和敏感性加权图像检测小静脉(
T-2*-weighted magnetic resonance imaging at 7 T has recently been shown to allow differentiation between white-matter multiple sclerosis lesions and asymptomatic white-matter lesions, by the presence or absence of a detectable central blood vessel. The aim of the present work is to improve the technique by increasing the sensitivity to veins at both 3 T and 7 T, and to assess the benefit of ultra-high-field imaging.Signal-to-noise ratio (SNR) measurements and simulations are used to compare the sensitivity of magnitude T-2*-weighted and susceptibility-weighted images for the detection of small veins (