Disparities in A1C Levels Between Hispanic and Non-Hispanic White Adults With Diabetes
Disparities in A1C Levels Between Hispanic and Non-Hispanic White Adults With Diabetes
复制标题
患有糖尿病的西班牙裔和非西班牙裔白人成人之间 A1C 水平的差异
作者：
J. Kirk;L. Passmore;R. Bell;K. Narayan;R. D'Agostino;T. Arcury;S. Quandt
西班牙裔的糖尿病和糖尿病相关并发症的发病率高于非西班牙裔白人。进行荟萃分析，以估计这两组A1 C平均值之间的差异。研究设计和方法-我们对1993年至2007年7月发表的文章进行了PubMed检索。数据来源包括PubMed、Web of Science、Cumulative Index to Nursing and Allied Health、科克伦图书馆、联合健康信息数据库和教育资源信息中心。提取了样本量、年龄、性别、A1 C、地理位置和研究设计的数据。纳入了西班牙裔和非西班牙裔白人糖尿病患者的临床试验和队列研究的横断面数据和基线数据。如果研究包括年龄<18岁的个体或患有糖尿病前期或妊娠糖尿病的患者，则将其排除。共审查了495项研究，其中73项包含西班牙裔和非西班牙裔白人的A1 C数据，11项符合纳入标准。荟萃分析显示，统计学显著性平均差异（P < 0.0001）为-0.46（95%CI-0.63至-0.33），与西班牙裔的A1 C高0.5%相关。按设计（横断面或队列）、A1 C数据收集方法（病历审查或血液采样）和护理类型（管理或非管理）进行的研究得出了相似的结果。结论：在这项荟萃分析中，西班牙裔糖尿病患者的糖化血红蛋白比非西班牙裔糖尿病患者高出0.5%。理解这种差异的原因应该是未来研究的重点。
OBJECTIVE—Hispanics have higher rates of diabetes and diabetes-related complications than do non-Hispanic whites. A meta-analysis was conducted to estimate the difference between the mean values of A1C for these two groups. RESEARCH DESIGN AND METHODS—We executed a PubMed search of articles published from 1993 through July 2007. Data sources included PubMed, Web of Science, Cumulative Index to Nursing and Allied Health, the Cochrane Library, Combined Health Information Database, and Education Resources Information Center. Data on sample size, age, sex, A1C, geographical location, and study design were extracted. Cross-sectional data and baseline data from clinical trials and cohort studies for Hispanics and non-Hispanic whites with diabetes were included. Studies were excluded if they included individuals <18 years of age or patients with pre-diabetes or gestational diabetes. RESULTS—A total of 495 studies were reviewed, of which 73 contained data on A1C for Hispanics and non-Hispanic whites, and 11 met the inclusion criteria. Meta-analysis revealed a statistically significant mean difference (P < 0.0001) of −0.46 (95% CI −0.63 to −0.33), correlating to an ∼0.5% higher A1C for Hispanics. Grouping studies by design (cross-sectional or cohort), method of data collection for A1C (chart review or blood sampling), and care type (managed or nonmanaged) yielded similar results. CONCLUSIONS—In this meta-analysis, A1C was ∼0.5% higher in Hispanic patients with diabetes than in non-Hispanic patients. Understanding the reasons for this disparity should be a focus for future research.
胰岛素和糖尿病。
DOI：
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发表时间：
1986
期刊：
Transactions of the Association of American Physicians
影响因子：
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作者：
Mako,ME;Rubenstein,AH
通讯作者：
Rubenstein,AH