Effects of Kakato-tsurutsuru socks on dry heels in healthy volunteer subjects.
Effects of Kakato-tsurutsuru socks on dry heels in healthy volunteer subjects.
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Kakato-tsurutsuru 袜子对健康志愿者受试者脚跟干燥的影响。
DOI：
10.1111/1346-8138.15235
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
Takamori K.
中科院分区：
文献类型：
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作者：
Kamo A;Umehara Y;Negi O;Iwata M;Kamata Y;Suga Y;Ogawa H;Tominaga M;Takamori K.
Kakato‐tsurutsuru（Kt）袜子在日本已经销售了近30年。穿着者声称他们改善脚跟干燥，尽管没有科学证据。我们通过问卷调查、临床评分和非侵入性皮肤测量研究了KT袜对足跟干燥的影响。在一项双盲、随机交叉研究中，10名健康志愿者连续4周穿着对照袜或Kt袜超过2周。在试验前和试验期间每周测量内侧和背侧足跟的皮肤水合和蒸发。皮肤科医生对脱皮和皮肤破裂的临床评价进行评分。采用视觉模拟量表（VAS）对舒适度、袜子气候湿度和皮肤干燥度进行问卷调查。Kt组舒适度VAS评分显著高于对照组。对照组和Kt组的平均Δ皮肤干燥度分别为-1.63和2.22，显示出显著改善。在足跟背侧的临床结果中，与对照组相比，Kt组的Δ脱皮和Δ破裂皮肤评分显著降低，Δ角质层水合作用显著增加。KT袜可以保留蒸发的汗水与天然保湿因子的成分，支持足跟角质层的持水能力。这些研究结果表明，KT袜可以改善足跟皮肤干燥。
Kakato‐tsurutsuru (Kt) socks have been selling for almost 30 years in Japan. Wearers claim they improve heel dryness despite no scientific evidence. We investigated the effects of Kt socks on heel dryness by questionnaire, clinical scores and non‐invasive skin measurements. In a double‐blind, randomized cross‐over study, 10 healthy volunteers wore control or Kt socks over 2 weeks in sequence for 4 weeks. Skin hydration and evaporation of the medial and dorsal heel were measured before and every week during the trial. Clinical evaluations of desquamation and cracked skin were scored by a dermatologist. A visual analog scale (VAS) questionnaire of comfort, sock climate humidity and skin dryness was conducted. The VAS of comfort was significantly higher in Kt than controls. Average Δskin dryness in control and Kt groups was −1.63 and 2.22, respectively, showing a significant improvement. In the clinical findings of the dorsal side of the heel, Δdesquamation and Δcracked skin scores were significantly decreased and Δstratum corneum hydration significantly increased in Kt compared with controls. Kt socks may retain evaporated sweat with components of natural moisturizing factors, supporting the water‐holding ability of the heel stratum corneum. These findings suggest that Kt socks may improve heel skin dryness.