Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
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DOI：
10.2169/internalmedicine.4176-19
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发表时间：
2020-01-01
影响因子：
1.2
通讯作者：
Shikata, Hisaharu
中科院分区：
文献类型：
--
作者：
Kaneko, Masahiko;Kazatani, Takurou;Shikata, Hisaharu
我们在此报告一位二十四岁男性建筑工人因职业性铅中毒而出现急腹症及正常红细胞性贫血。尿δ-氨基乙酰丙酸和游离红细胞原卟啉水平升高，而尿胆色素原水平无任何增加。检测到血铅水平升高100微克/分升，证实了铅中毒的诊断。用乙二胺四乙酸二钠钙进行螯合治疗，临床症状和血铅水平迅速改善。临床医生应该意识到，在日本，由职业暴露引起的铅中毒仍然会在建筑工人中零星发生。
We herein report a 24-year-old male construction worker with occupational lead poisoning who presented with acute abdomen and normocytic anemia. The levels of urinary delta-aminolevulinic acid and free erythrocyte protoporphyrin were elevated without any increase in the level of urine porphobilinogen. Detection of an elevated blood lead level of 100 mu g/dL confirmed a diagnosis of lead poisoning. Chelation therapy with calcium disodium ethylenediaminetetraacetate resulted in prompt improvement of the clinical symptoms and the blood lead level. Clinicians should be aware that lead poisoning caused by occupational exposure can still occur sporadically in construction workers in Japan.