Human immunodeficiency virus reverse transcriptase and protease sequence database
Human immunodeficiency virus reverse transcriptase and protease sequence database
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DOI：
10.1093/nar/28.1.346
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发表时间：
2000-01-01
影响因子：
14.9
通讯作者：
Gonzales, MJ
中科院分区：
文献类型：
--
作者：
Shafer, RW;Jung, DR;Gonzales, MJ
HIV RT和蛋白酶序列数据库是一个在线关系数据库，其对进化和药物相关的人类免疫缺陷病毒（HIV）逆转录酶（RT）和蛋白酶序列变异进行编目（hivdb.stanford.edu）。该数据库包含几乎所有已发表的HIV RT和蛋白酶序列的汇编，包括国际合作数据库提交（例如，序列与关于序列样品的来源和从其获得分离物的个体的抗逆转录病毒药物治疗史的数据相关联。数据库是精心策划的，并且序列用来自>230篇参考文献的数据进行注释。用户可以检索额外的数据，并查看符合特定标准（例如，治疗史，亚型，特定突变的存在）的序列集的比对，基因特异性序列分析程序，新的用户定义的查询和近2000个额外的序列在1999年被添加。
The HIV RT and Protease Sequence Database is an online relational database that catalogs evolutionary and drug-related human immunodeficiency virus (HIV) reverse transcriptase (RT) and protease sequence variation (http://hivdb.stanford.edu), The database contains a compilation of nearly all published HIV RT and protease sequences including International Collaboration database submissions (e.g., GenBank) and sequences published in journal articles, Sequences are linked to data about the source of the sequence sample and the antiretroviral drug treatment history of the individual from whom the isolate was obtained, The database is curated and sequences are annotated with data from >230 literature references. Users can retrieve additional data and view alignments of sequence sets meeting specific criteria (e.g,, treatment history, subtype, presence of a particular mutation), A gene-specific sequence analysis program, new user-defined queries and nearly 2000 additional sequences were added in 1999.