Measurement of Intraocular Pressure Using the NT-4000: A New Non-Contact Tonometer Equipped with Pulse Synchronous Measurement Function
Measurement of Intraocular Pressure Using the NT-4000: A New Non-Contact Tonometer Equipped with Pulse Synchronous Measurement Function
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DOI：
10.1097/01.ijg.0000159120.03747.48
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发表时间：
2005-06
影响因子：
2
通讯作者：
K. Yaoeda;M. Shirakashi;Atsushi Fukushima;S. Funaki;H. Funaki;Nobutaka Ofuchi;T. Nakatsue;H. Abe
中科院分区：
文献类型：
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作者：
K. Yaoeda;M. Shirakashi;Atsushi Fukushima;S. Funaki;H. Funaki;Nobutaka Ofuchi;T. Nakatsue;H. Abe
用途：NT-4000（Nidek Co. Ltd.，Gamagori，Japan）是一种新型非接触式眼压计（NCT），配备了脉搏同步测量功能，可以测量与眼脉搏同步的眼内压（IOP）。本研究的目的是评估NT-4000在正常受试者和青光眼和高眼压患者中的有用性。方法：175例175只眼。首先，使用不具有脉冲同步测量功能（NTn）的NT-4000测量IOP。其次，使用具有脉搏同步测量功能的NT-4000测量脉搏信号的峰、中、谷相位的IOP（分别为NTp、NTm、NTt）。用Goldmann压平眼压计（GT）测量眼压。NCT测量中三个读数的变异系数（CV）用于评价会话内再现性。使用Wilcoxon符号秩检验和单因素方差分析与Scheffe检验进行统计学比较。采用线性回归分析计算相关系数。P值小于0.05被认为具有统计学显著性。结果：NTn、NTp、NTm和NTt的变异系数分别为6.4%、5.5%、4.9%和5.2%。NTp、NTm、NTt的变异系数均显著小于NTn（P = 0.007，P < 0.001，P < 0.001）。NTp显著高于NTt（P = 0.038）。GT与NTn、NTp、NTm、NTt呈显著正相关（r = 0.898，P < 0.001; r = 0.912，P < 0.001; r = 0.908，P < 0.001; r = 0.900，P < 0.001）。结论：NT-4000可检测与眼脉动相关的眼压波动。
Purpose:NT-4000 (Nidek Co. Ltd., Gamagori, Japan) is a new non-contact tonometer (NCT) equipped with pulse synchronous measurement function that can measure intraocular pressure (IOP) synchronized with the ocular pulse. The purpose of this study was to evaluate the usefulness of NT-4000 in normal subjects and in patients with glaucoma and ocular hypertension. Methods:This study included 175 eyes of 175 subjects. Firstly, the IOP was measured using NT-4000 without the pulse synchronous measurement function (NTn). Secondly, the IOP at peak, middle, and trough phases of the pulse signal were measured using NT-4000 with the pulse synchronous measurement function (NTp, NTm, NTt, respectively). Additionally, the IOP was measured with Goldmann applanation tonometer (GT). The coefficient of variation (CV) of three readings in the NCT measurements was used to evaluate the intra-session reproducibility. Statistical comparisons were performed using Wilcoxon signed rank test and one-way analysis of variance with Scheffe's test. Linear regression analysis was used to calculate correlation coefficients. P values less than 0.05 were accepted as statistically significant. Results:The CV of NTn, NTp, NTm, and NTt were 6.4%, 5.5%, 4.9%, and 5.2%, respectively. The CV of NTp, NTm, and NTt were significantly smaller than that of NTn (P = 0.007, P < 0.001, P < 0.001, respectively). NTp was significantly higher than NTt (P = 0.038). GT was significantly correlated with NTn, NTp, NTm, and NTt (r = 0.898, P < 0.001; r = 0.912, P < 0.001; r = 0.908, P < 0.001; r = 0.900, P < 0.001, respectively). Conclusion:NT-4000 can detect the fluctuation of IOP associated with the ocular pulse.