Multilanthanide Systems for Medical Imaging Applications.
Multilanthanide Systems for Medical Imaging Applications.
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DOI：
10.2174/1877912311101020088
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发表时间：
2011-12-01
期刊：
影响因子：
--
通讯作者：
Allen MJ
中科院分区：
文献类型：
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作者：
Moore JD;Allen MJ
含有多个镧系元素离子的分子在医学成像应用中具有独特的潜力，包括磁共振成像（MRI）和荧光成像领域。对多镧系元素络合物作为 MRI 造影剂和生物响应荧光探针的研究使人们更好地了解了控制这些络合物行为的结构特征。本综述将调查过去五年多核稀土配合物的进展，特别关注影响潜在医学成像应用的结构参数。本综述中引用的专利来自过去五年，描述了含有多种镧系离子的造影剂。
Molecules containing multiple lanthanide ions have unique potential in applications for medical imaging including the areas of magnetic resonance imaging (MRI) and fluoresence imaging. The study of multilanthanide complexes as contrast agents for MRI and as biologically responsive fluorescent probes has resulted in an improved understanding of the structural characteristics that govern the behavior of these complexes. This review will survey the last five years of progress in multinuclear lanthanide complexes with a specific focus on the structural parameters that impact potential medical imaging applications. The patents cited in this review are from the last five years and describe contrast agents that contain multiple lanthanide ions.