Reversed urban-rural differences in breast cancer mortality (China, 2002-2008)
Reversed urban-rural differences in breast cancer mortality (China, 2002-2008)
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DOI：
10.1007/s10549-010-1276-2
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发表时间：
2011-02-01
影响因子：
3.8
通讯作者：
Hu, Guoqing
中科院分区：
文献类型：
--
作者：
He, Min;Guo, Qulian;Hu, Guoqing
本研究的目的是调查2002年至2008年中国地区乳腺癌死亡率的城乡差异。对死亡率数据进行纵向分析。死亡率数据摘自《中国卫生统计年鉴》。用线性回归检验死亡率的线性趋势的统计学意义。比率的变化百分比被用来衡量线性趋势，其计算方法是回归系数x 100 x 6除以2002年的比率。2002至2008年间，城市妇女的乳腺癌死亡率上升了201%(P<；0.05)，而农村妇女的死亡率并未出现显著上升，从而扭转了城乡差别(从2002年的-2.3/10万人增加到2008年的3.6人)。亚组分析表明，城乡差距的逆转完全是由于55-59岁和75岁及以上城市妇女的大幅增加。此外，35-49岁的城市妇女和35-39岁的农村妇女的乳腺癌死亡率显著下降(P<；0.05)。2002-2008年期间，乳腺癌死亡率的城乡差距缩小，主要原因是城市老年妇女的增加。还需要进一步的研究来了解增加的情况，并为中国的城市老年妇女制定具有成本效益的干预措施。
The purpose of this study was to examine the urban-rural difference in breast cancer mortality between 2002 and 2008 in China. A longitudinal analysis of mortality data was performed. Mortality data were extracted from Chinese Health Statistics Yearbook. Linear regression was used to examine the statistical significance of linear trend in mortality rates. The percent change in rates was used to measure the linear trend, which was calculated as regression coefficient x 100 x 6 divided by the rate of 2002. Between 2002 and 2008, the mortality from breast cancer increased by 201% among urban women (P < 0.05) while among rural women the rate did not show the significant increase, thus resulting in a reversed urban-rural difference (from -2.3/100,000 population in 2002 to 3.6 in 2008). Subgroup analysis showed that the reversed urban-rural difference was completely due to substantial increases among urban women aged 55-59 years and aged 75 years and above. In addition, significant decreases of breast cancer mortality were observed in urban women aged 35-49 years and in rural women aged 35-39 years (P < 0.05). The reversed urban-rural difference in breast cancer mortality during 2002-2008 is primarily caused by the increases among elderly urban women. Further studies are needed to understand the increases and to develop cost-effective interventions for elderly urban women in China.