SINGLE-UNIT ACTIVITY IN THE LATERAL NUCLEUS OF THE AMYGDALA AND OVERLYING AREAS OF THE STRIATUM IN FREELY BEHAVING RATS - RATES, DISCHARGE PATTERNS, AND RESPONSES TO ACOUSTIC STIMULI
SINGLE-UNIT ACTIVITY IN THE LATERAL NUCLEUS OF THE AMYGDALA AND OVERLYING AREAS OF THE STRIATUM IN FREELY BEHAVING RATS - RATES, DISCHARGE PATTERNS, AND RESPONSES TO ACOUSTIC STIMULI
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DOI：
10.1037/0735-7044.107.5.757
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发表时间：
1993-10-01
影响因子：
1.9
通讯作者：
PAVLIDES, C
中科院分区：
文献类型：
--
作者：
BORDI, F;LEDOUX, J;PAVLIDES, C
在清醒、自由活动的大鼠扁桃体外侧核（AL）中检测了单个单元的声学反应。录音是由一束可移动的9根微细导线制成的。大多数细胞的自发活动率很低（平均约为3个峰值/秒）。在睡眠状态下，放电频率增加。在AL的背侧亚核（ALd）中发现了短潜伏期听觉反应（12-25 ms）。ALd中的细胞最典型的反应是持续的。ALd中的一些细胞表现出对高频、音调爆发或中心频率高于12khz的调频刺激的偏好。杏仁核其他区域的反应潜伏期要长得多。我们的结果证实了先前一项研究（F. Bordi & J. LeDoux, 1992）的主要发现，该研究检测了麻醉大鼠AL中单个细胞的声反应特性。清醒和麻醉大鼠的研究结果提供了迄今为止有关杏仁核神经元感觉处理的最精确信息。
Acoustic responses of single units were examined in awake, freely behaving rats in the lateral nucleus of the amygdala (AL). Recordings were made from a movable bundle of 9 microwires. Most cells had very low rates of spontaneous activity (about 3 spikes/s on average). Firing rates increased during sleep states. Short-latency auditory responses (12-25 ms) were found in the dorsal subnucleus (ALd) of the AL. Cells in the ALd most typically responded in a sustained fashion. Some of the cells in the ALd showed preferences for high frequencies, tone bursts, or frequency-modulated stimuli with center frequencies above 12 kHz. Response latencies were considerably longer in other areas of the amygdala. Our results corroborate the main findings of a previous study (F. Bordi & J. LeDoux, 1992) that examined the acoustic response properties of single cells in the AL in anesthetized rats. Together the findings from awake and anesthetized rats provide the most precise information about sensory processing in amygdala neurons available to date.