Association of Streptococcus bovis bacteremia with colonic neoplasia and extracolonic malignancy
Association of Streptococcus bovis bacteremia with colonic neoplasia and extracolonic malignancy
复制标题
DOI：
10.1001/archsurg.139.7.760
复制
发表时间：
2004-07-01
影响因子：
--
通讯作者：
Salem, RR
中科院分区：
文献类型：
--
作者：
Gold, JS;Bayar, S;Salem, RR
背景资料：牛链球菌菌血症与结肠肿瘤之间的关系已被很好地描述;然而，牛链球菌菌血症与结肠外肿瘤之间的关系尚未得到很好的评价。假设：牛链球菌菌血症可能与结肠肿瘤和结肠外恶性肿瘤有关。设计：回顾性分析所有通过计算机细菌学记录检索确定的牛链球菌菌血症病例。设置：一家三级转诊医院和一家位于同一城市的社区医院。（41名成人，4名儿童）在12年的时间内被证实患有牛链球菌菌血症。对可用的患者记录进行了审查，以确定结肠肿瘤的存在，胃肠道内窥镜检查的使用，结果：17例患者（41%的成人患者）进行了结肠镜检查。16名患者（39%的成人）存在结肠肿瘤，其中3名患者患有浸润性结直肠癌（7%的成人）。13例患者（32%的成人）存在浸润性癌症。8例恶性病变发生在胃肠道，5例肠外malignances.Conclusion：牛链球菌菌血症与结肠肿瘤和结肠外恶性肿瘤。
Background: The association between Streptococcus bovis bacteremia and colonic neoplasia is well described; however, the relationship between S bovis and neoplasia outside the colon has not been well evaluated.Hypothesis: S bovis bacteremia may be associated with colonic neoplasia and extracolonic malignancy.Design: Retrospective review of all documented cases of S bovis bacteremia identified by a search of computerized bacteriology records.Setting: One tertiary referral hospital and 1 community hospital located in the same city.Patients: Forty-five patients (41 adults, 4 children) with documented S bovis bacteremia during a 12-year period were identified.Main Outcome Measures: Available patient records were reviewed to identify the presence of colonic neoplasia, the use of gastrointestinal endoscopy, and the presence of gastrointestinal or extraintestinal malignancies.Results: Seventeen patients (41% of adult patients) underwent colonoscopy. Colonic neoplasia was present in 16 patients (39% of adults), with 3 of these patients having invasive colorectal cancer (7% of adults). Invasive cancer was present in 13 patients (32% of adults). Eight patients had malignant lesions arising within the gastrointestinal tract, and 5 patients had extraintestinal malignancies.Conclusion: S bovis bacteremia is associated with both colonic neoplasia and extracolonic malignancy.