Interest of pelvic and paraaortic lymphadenectomy in patients with stage IB and II cervical carcinoma
Interest of pelvic and paraaortic lymphadenectomy in patients with stage IB and II cervical carcinoma
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DOI：
10.1006/gyno.1998.5308
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发表时间：
1999-04-01
影响因子：
4.7
通讯作者：
Duvillard, P
中科院分区：
文献类型：
--
作者：
Morice, P;Castaigne, D;Duvillard, P
目标.本研究的目的是评估在Ib和II期宫颈癌患者中系统性盆腔和腹主动脉旁淋巴结清扫术的兴趣和潜在的治疗价值。本文对1985 ~ 1994年间421例宫颈癌患者进行了前瞻性研究，这些患者均接受了放射治疗和手术联合盆腔和腹主动脉旁淋巴结清扫术。盆腔淋巴结受累率为26%（106例患者），主动脉旁转移率为8%（32例患者）。单侧盆腔淋巴结受累率为14%（59例患者），双侧盆腔淋巴结受累率为11%（47例患者）。12%（52例患者）发现肉眼可见的阳性淋巴结。在一个单变量分析中，一个年轻的年龄（
Objectives. The objectives of this study were to evaluate the interest and the potential therapeutic value of systematic pelvic and paraaortic lymphadenectomy in patients with stage Ib and II cervical carcinoma.Methods. This was a prospective study including 421 patients with cervical cancer treated, from 1985 to 1994, by combined radiation therapy and surgery with systematic pelvic and paraaortic lymphadenectomy.Results. The overall rate of pelvic lymph-node involvement was 26% (106 patients), and the rate of paraaortic metastases was 8% (32 patients). Pelvic nodal involvement was unilateral in 14% (59 patients) and bilateral in 11% (47 patients). Macroscopic positive nodes were found in 12% (52 patients). In a univariate analysis, a young age (