New approach to peripheral nerve injury: nutritional therapy
New approach to peripheral nerve injury: nutritional therapy
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DOI：
10.1080/1028415x.2018.1554322
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发表时间：
2020-10-02
影响因子：
3.6
通讯作者：
ozata Uyar, Gizem
中科院分区：
文献类型：
--
作者：
Yildiran, Hilal;Macit, Melahat Sedanur;ozata Uyar, Gizem
综述目的：目前尚无关于营养相关因素对周围神经损伤影响的文献综述。因此，本研究旨在评价营养因素对神经损伤的影响。最近的发现：尽管营养和营养因素影响个体的基本机制有几个，但它们对神经发生的确切影响还没有明确的确定。近年来，一些研究表明，某些营养素由于具有神经保护作用，在神经损伤中起着重要作用。除了手术治疗外，在周围神经损伤中，这些营养物质还可能在保护神经功能和健康以及恢复受损神经组织方面发挥作用。欧米伽3和欧米伽6脂肪酸、B组维生素、抗氧化剂、几种矿物质、酚类化合物和α-硫辛酸被认为对神经系统有影响。除此之外，肠道微生物区系对神经系统有影响，一些与营养相关的因素也可以通过肠道微生物区系影响神经发生。摘要：周围神经损伤是指周围神经系统的神经受损。周围神经损伤后，由于运动神经元再生障碍、雪旺细胞缺乏生存环境、神经再生能力差等原因，周围神经难以修复。与营养有关的因素，其影响在最近几年被描述，应该更多地考虑到。
Purpose of review:There is no review in the literature on the effect of nutrition-related factors on peripheral nerve injuries. Therefore, it is aimed to evaluate the effect of nutritional factors on nerve injuries in this compilation. Recent findings:Although there are several fundamental mechanisms by which nutrients and nutritional factors influence individuals, their exact impacts on neurogenesis have not been clearly identified. Recently, some studies showed that some nutrients have an important role in nerve injuries due to their neuroprotective properties. In addition to surgical treatment, in peripheral nerve injuries, these nutrients also may play a role in preserving nerve function and health, as well as in the recovery of an injured nerve tissue. Omega 3 and omega 6 fatty acids, group B vitamins, antioxidants, several minerals, phenolic compounds, and alpha lipoic acid are thought to have impacts on the nervous system. In addition to all of these, gut microbiota has effects on the nervous system, and some nutrient-related factors can also affect neurogenesis via gut microbiota. Summary:Peripheral nerve injury is a condition in which the nerves in the peripheral nervous system become damaged. After the trauma, the peripheral nerve is hardly repaired due to the following reasons; the disability of the regeneration of motor neurons, the lack of a survival environment for Schwann cells, and the poor ability of the nerves to regenerate. Nutrition-related factors, the effects of which were described in recent years, should be more taken into account more.