Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection.
Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection.
复制标题
英国家庭绵羊的爱imeria和弯曲杆菌感染动态的决定因素：共同感染的作用。
DOI：
10.1017/s0031182021000044
复制
发表时间：
2021-04
期刊：
影响因子：
2.4
通讯作者：
Birtles, Richard J.
中科院分区：
文献类型：
--
作者：
Al-Neama, Raed Taha;Bown, Kevin J.;Blake, Damer P.;Birtles, Richard J.
由艾美耳球虫引起的球虫病是一种公认的家畜疾病。肠道艾美耳球虫感染很常见，但疾病通常只在感染强度异常高时才会出现。弯曲杆菌属是重要的人畜共患肠道细菌病原体，家畜是其重要的贮存宿主。在英格兰西北部的两个农场，绵羊艾美耳球虫和弯曲杆菌感染的多样性和流行病学进行了探讨，通过24个月的调查，在绵羊粪便脱落。大多数动物感染了10种不同艾美耳球虫中的至少一种，其中E. bakuensis和E. ovinoidalis最为常见。动物的年龄和采样季节与艾美耳球虫感染的概率和强度相关。采样季节也与弯曲杆菌感染的概率有关。有趣的是，较高强度的艾美耳球虫感染在未与弯曲杆菌共感染的动物中显著更常见。探讨了E. bakuensis和E. ovinoidalis感染，观察到感染任何一种都会显着增加感染另一种的可能性。E.感染弯曲杆菌的绵羊的ovinoidalis感染率显著降低。认识到共同感染者会影响寄生虫感染的动态，这与设计有效的感染控制方案有关。
Coccidiosis caused by Eimeria species is a well-recognized disease of livestock. Enteric Eimeria infections are common, but disease usually only manifests when infection intensity is abnormally high. Campylobacter species are important zoonotic enteric bacterial pathogens for which livestock are important reservoir hosts. The diversity and epidemiology of ovine Eimeria and Campylobacter infections on two farms in north-western England were explored through a 24-month survey of shedding in sheep feces. Most animals were infected with at least one of 10 different Eimeria species, among which E. bakuensis and E. ovinoidalis were most common. An animal's age and the season of sampling were associated with the probability and intensity of Eimeria infection. Season of sampling was also associated with the probability of Campylobacter infection. Interestingly, higher intensities of Eimeria infections were significantly more common in animals not co-infected with Campylobacter. We explored the determinants of E. bakuensis and E. ovinoidalis infections, observing that being infected with either significantly increased the likelihood of infection with the other. The prevalence of E. ovinoidalis infections was significantly lower in sheep infected with Campylobacter. Recognition that co-infectors shape the dynamics of parasite infection is relevant to the design of effective infection control programmes.