Electrochemical Fabrication of Cobalt Oxides/Nanoporous Gold Composite Electrode and its Nonenzymatic Glucose Sensing Performance
Electrochemical Fabrication of Cobalt Oxides/Nanoporous Gold Composite Electrode and its Nonenzymatic Glucose Sensing Performance
复制标题
氧化钴/纳米孔金复合电极的电化学制备及其非酶葡萄糖传感性能
DOI：
10.1002/elan.201501177
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发表时间：
2016
期刊：
影响因子：
3
通讯作者：
Li Zelin
中科院分区：
文献类型：
--
作者：
Zhou Chaohui;Tang Xueyong;Xia Yue;Li Zelin
以六氰合铁酸钴（CoHCF）为前体，在纳米多孔金电极（NPG）上修饰钴氧化物（CoOx），成功构建了非酶葡萄糖传感器。它具有高灵敏度和长期稳定性，以及对人血清样品中葡萄糖浓度的满意定量。仔细表征所得CoOx/NPG的形态和表面分析。采用循环伏安法和安培法两种检测方法研究了CoOx/NPG在碱性溶液中的葡萄糖传感性能。使用循环伏安法，在−0.5 V时，葡萄糖部分氧化峰电流与葡萄糖浓度呈线性关系，直至14 mM，灵敏度为283.7 µA mM−1cm−2。 在2 µM至2 mM葡萄糖浓度范围内，在0.55 V下获得线性安培响应，灵敏度为2025µA mM− 1 cm − 2，响应时间<3 s。
A nonenzymatic glucose sensor was successfully established by electrochemically decorating cobalt oxides (CoOx) on a nanoporous gold electrode (NPG) using cobalt hexacyanoferrate (CoHCF) as a precursor. It exhibited high sensitivity and long‐term stability as well as satisfactory quantification of glucose concentration in human serum samples. The morphology and surface analysis of the resulting CoOx/NPG were carefully characterized. Two detection methods, cyclic voltammetry and amperometry, were employed to evaluate the performance of CoOx/NPG towards glucose sensing in alkaline solution. Using cyclic voltammetry, at −0.5 V, the glucose partial oxidation peak current is linear to the glucose concentration up to 14 mM with a sensitivity of 283.7 µA mM−1cm−2. A linear amperometric response at 0.55 V was obtained in the glucose concentration range from 2 µM to 2 mM with a sensitivity of 2025 µA mM−1cm−2and a response time <3 s.