Concepts in advanced renal carcinoma.
Concepts in advanced renal carcinoma.
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DOI：
10.1016/j.soncn.2012.05.006
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发表时间：
2012-08-01
影响因子：
2.2
通讯作者：
Esper, Peg
中科院分区：
文献类型：
--
作者：
Esper, Peg
目的：在过去的6年中，由于对肾癌生物学的理解的提高以及针对肿瘤进展相关通路的治疗方法的发展，晚期肾细胞癌的治疗选择急剧增加。治疗晚期肾细胞癌的新疗法需要证据-在讨论治疗选择时，基于决策。了解治疗策略、拟定的作用机制、潜在不良事件，和管理策略为护士提供了一个基础，以提供适当的病人教育和有效的管理治疗相关的副作用，帮助病人最大限度地提高临床效果。
OBJECTIVES: Treatment options for advanced renal cell carcinoma have increased dramatically over the past 6 years as a result of improved understanding of the biology of renal cancer and the development of therapies to target pathways relevant to tumor progression.DATA SOURCES: Research-based articles.CONCLUSION: New therapies to treat advanced renal cell cancer results in a need for evidence-based decision making when discussing treatment choices.IMPLICATIONS FOR NURSING PRACTICE: Knowledge of therapeutic strategies, their proposed mechanism of action, potential adverse events, and management strategies provides nurses with a foundation to provide appropriate patient education and effective management of treatment-related side effects, assisting patients to maximize clinical outcomes.