Incentivized recruitment of a population sample to a mobile HIV testing service increases the yield of newly diagnosed cases, including those in need of antiretroviral therapy.

Incentivized recruitment of a population sample to a mobile HIV testing service increases the yield of newly diagnosed cases, including those in need of antiretroviral therapy.
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DOI:
10.1111/j.1468-1293.2011.00947.x
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发表时间:
2012-02
期刊:
影响因子:
3
通讯作者:
Bekker LG
Bekker LG
中科院分区:
医学4区
文献类型:
--
作者:
Kranzer K;Govindasamy D;van Schaik N;Thebus E;Davies N;Zimmermann M;Jeneker S;Lawn S;Wood R;Bekker LG

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该研究的目的是比较新诊断的艾滋病毒感染和晚期免疫缺陷病例的产量之间的个人参加移动的艾滋病毒咨询和检测(HCT)服务的参与者在人口为基础的艾滋病毒血清阳性率调查和那些访问相同的服务作为志愿者进行常规检测。这项研究是在南非开普敦大都会区的一个城郊乡镇进行的。随机选择调查参与者(招募的测试者),对其进行家访,并邀请其参加移动的HCT服务。他们因参与调查而获得70张南非兰德食品券,但可以选择匿名测试。将艾滋病毒诊断率与在调查前自愿参加同一艾滋病毒检测设施且未获得奖励(自愿检测者)的社区成员中检测到的艾滋病毒诊断率进行比较。共有1813人被纳入分析(936名招募人员和877名自愿测试人员)。新诊断的HIV感染率在招募的测试者中为10.9% [95%置信区间(CI)9.0-13.1%],在自愿测试者中为5.0%(3.7-6.7%)。在招募和自愿测试者中,严重免疫缺陷(CD 4计数≤200个细胞/μL)的患病率分别为17.8%(10.9-26.7%)和4.6%(0.0-15.4%)。在招募的CD 4计数≤350个细胞/μL的测试者中,与HIV护理的关联为78.8%。与常规自愿HCT相比,选择和邀请结合激励措施使新诊断的艾滋病毒感染率增加了一倍,并使需要抗逆转录病毒治疗的个人感染率增加了近四倍。这可能是增加社区艾滋病毒诊断和获得护理的一项重要战略。
The aim of the study was to compare the yields of newly diagnosed cases of HIV infection and advanced immunodeficiency between individuals attending a mobile HIV counselling and testing (HCT) service as participants in a population-based HIV seroprevalence survey and those accessing the same service as volunteers for routine testing. The study was conducted in a peri-urban township within the Cape Metropolitan Region, South Africa. Survey participants (recruited testers) were randomly selected, visited at home and invited to attend the mobile HCT service. They received 70 South African Rand food vouchers for participating in the survey, but could choose to test anonymously. The yield of HIV diagnoses was compared with that detected in members of the community who voluntarily attended the same HIV testing facility prior to the survey and did not receive incentives (voluntary testers). A total of 1813 individuals were included in the analysis (936 recruited and 877 voluntary testers). The prevalence of newly diagnosed HIV infection was 10.9% [95% confidence interval (CI) 9.0–13.1%] among recruited testers and 5.0% (3.7–6.7%) among voluntary testers. The prevalence of severe immune deficiency (CD4 count ≤200 cells/μL) among recruited and voluntary testers was 17.8% (10.9–26.7%) and 4.6% (0.0–15.4%), respectively. Linkage to HIV care in recruited testers with CD4 counts ≤350 cells/μL was 78.8%. Compared with routine voluntary HCT, selection and invitation in combination with incentives doubled the yield of newly diagnosed HIV infections and increased the yield almost fourfold of individuals needing antiretroviral therapy. This may be an important strategy to increase community-based HIV diagnosis and access to care.
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