Comparison Between Serum hsCRP and LDL Cholesterol for Search of a Better Predictor for Ischemic Heart Disease
Comparison Between Serum hsCRP and LDL Cholesterol for Search of a Better Predictor for Ischemic Heart Disease
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DOI：
10.1007/s12291-010-0100-4
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发表时间：
2011-04-01
影响因子：
2.1
通讯作者：
Prasad, K. R.
中科院分区：
文献类型：
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作者：
Datta, Subinay;Iqbal, Zahidul;Prasad, K. R.
急性心肌梗塞是世界范围内发病和死亡的主要原因之一，动脉粥样硬化是缺血性心脏病的主要原因。为了确定更好的动脉粥样硬化临床标志物，我们评估了血清低密度脂蛋白（LDL-C）和超敏C反应蛋白（hsCRP）。研究人员对 100 名心肌梗塞患者和 100 名对照组（无论年龄和性别）进行了为期 2 年的研究。统计分析显示，心肌梗死组血清hsCRP较对照组显着升高（P < 0.01），而LDL-C则无显着升高（P > 0.05）。我们的结论是，血清hsCRP对动脉粥样硬化的风险具有更好的预测价值。
Acute myocardial Infarction is one of the major causes of morbidity & mortality in world and atherosclerosis is the major cause of ischemic heart disease. In order to determine the better clinical marker of atherosclerosis, we estimated serum low-density lipoprotein (LDL-C) and high sensitivity C-reactive protein (hsCRP). Hundred patients of myocardial infarction and 100 controls irrespective of age and sex were studied for these parameters over a period of 2 years. The statistical analysis showed that the serum hsCRP was significantly raised in myocardial infarction cases than controls (P < 0.01) but LDL-C was not (P > 0.05). We conclude that the serum hsCRP has better predictive value for risk of atherosclerosis.