Anorexia Nervosa: Towards An Integrative Neuroscience Model
Anorexia Nervosa: Towards An Integrative Neuroscience Model
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DOI：
10.1002/erv.974
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发表时间：
2010-05-01
影响因子：
5.3
通讯作者：
Williams, L. M.
中科院分区：
文献类型：
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作者：
Hatch, A.;Madden, S.;Williams, L. M.
我们从行为、认知、生物和遗传领域的研究中回顾了神经性厌食症（AN）中与情绪相关的紊乱的证据。这些领域被整合到一个综合神经科学模型的框架内，该模型强调情绪和感觉及其在大脑组织中的调节作用。我们进行了 PsychInfo 和 Medline 搜索，以确定每个领域内 AN 上已发表的同行评审论文。这篇综述揭示了 AN 中从无意识到意识过程的“情绪”、“思考和感觉”和“自我调节”障碍的证据。然后应用综合神经科学框架来开发 AN 模型，从中生成实证研究的假设。我们认为，AN 反映了信息处理最早阶段的核心情绪干扰，随后对后期的思维、感觉和自我调节阶段产生影响。版权所有 (C) 2009 John Wiley & Sons, Ltd 和饮食失调协会。
We reviewed the evidence for emotion-related disturbances in anorexia nervosa (AN) from behavioural, cognitive, biological and genetic domains of study. These domains were brought together within the framework of an integrative neuroscience model that emphasizes the role of emotion and feeling and their regulation, in brain organization. PsychInfo and Medline searches were performed to identify published peer-reviewed papers on AN within each domain. This review revealed evidence for 'Emotion', 'Thinking and Feeling' and 'Self-regulation' disturbances in AN that span non-conscious to conscious processes. An integrative neuroscience framework was then applied to develop a model of AN, from which hypotheses for empirical investigation are generated. We propose that AN reflects a core disturbance in emotion at the earliest time stage of information processing with subsequent effects on the later stages of thinking, feeling and self-regulation. Copyright (C) 2009 John Wiley & Sons, Ltd and Eating Disorders Association.