Depression of cardiac function by bisantrene.
Depression of cardiac function by bisantrene.
复制标题
比生群抑制心脏功能。
DOI：
10.1097/00007611-198512000-00029
复制
发表时间：
1985
影响因子：
1.1
通讯作者：
Parrish,MD
中科院分区：
文献类型：
--
作者：
Artman,M;Roloff,JS;Olson,RD;Parrish,MD
Bisantrene is a newer anthracycline derivative currently being investigated in phase 2 trials. One presumed advantage of bisantrene is that it is purportedly free of cardiotoxic effects. However, bisantrene apparently precipitated congestive heart failure after a single intravenous infusion in a young boy, prompting our study of a second child who remained asymptomatic but had transient declines in cardiac function after receiving bisantrene. Since bisantrene may acutely depress myocardial contractile function, further investigation is necessary.
