CONTROLLED TRIAL OF FASTING AND ONE-YEAR VEGETARIAN DIET IN RHEUMATOID-ARTHRITIS
CONTROLLED TRIAL OF FASTING AND ONE-YEAR VEGETARIAN DIET IN RHEUMATOID-ARTHRITIS
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DOI：
10.1016/0140-6736(91)91770-u
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发表时间：
1991-10-12
期刊：
影响因子：
168.9
通讯作者：
FORRE, O
中科院分区：
文献类型：
--
作者：
KJELDSENKRAGH, J;HAUGEN, M;FORRE, O
禁食是治疗类风湿性关节炎的有效方法，但大多数患者在重新进食后会复发。在一项随机的单盲对照试验中，对禁食一年后素食的效果进行了评估。27名患者被分配到一家健康农场住四周。在最初的7-10天的部分禁食后，他们被要求进行单独调整的无麸质素食饮食，为期3.5个月。在接下来的研究中，这些食物逐渐改变为乳素饮食。对照组26名患者在疗养院住了四周，但在整个研究期间都吃普通饮食。在健康农场治疗四周后，节食组在压痛关节数、Ritchie关节指数、关节肿胀数、疼痛评分、晨僵持续时间、握力、血沉、C反应蛋白、白细胞计数和健康评估问卷评分方面均有显著改善。在对照组中，只有疼痛评分有显著改善。一年后，节食组的益处仍然存在，整个疗程的评估显示，节食组在所有测量的指标上都有显著的优势。这种饮食方案似乎是类风湿关节炎常规内科治疗的有效补充。
Fasting is an effective treatment for rheumatoid arthritis, but most patients relapse on reintroduction of food. The effect of fasting followed by one year of a vegetarian diet was assessed in a randomised, single-blind controlled trial.27 patients were allocated to a four-week stay at a health farm. After an initial 7-10 day subtotal fast, they were put on an individually adjusted gluten-free vegan diet for 3.5 months. The food was then gradually changed to a lactovegetarian diet for the remainder of the study. A control group of 26 patients stayed for four weeks at a convalescent home, but ate an ordinary diet throughout the whole study period. After four weeks at the health farm the diet group showed a significant improvement in number of tender joints, Ritchie's articular index, number of swollen joints, pain score, duration of morning stiffness, grip strength, erythrocyte sedimentation rate, C-reactive protein, white blood cell count, and a health assessment questionnaire score. In the control group, only pain score improved significantly. The benefits in the diet group were still present after one year, and evaluation of the whole course showed significant advantages for the diet group in all measured indices.This dietary regimen seems to be a useful supplement to conventional medical treatment of rheumatoid arthritis.