Plant-Pathogen Effectors: Cellular Probes Interfering with Plant Defenses in Spatial and Temporal Manners.
Plant-Pathogen Effectors: Cellular Probes Interfering with Plant Defenses in Spatial and Temporal Manners.
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DOI：
10.1146/annurev-phyto-080615-100204
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发表时间：
2016-08-04
影响因子：
10.2
通讯作者：
Coaker G
中科院分区：
文献类型：
--
作者：
Toruño TY;Stergiopoulos I;Coaker G
植物拥有大量的免疫受体，能够识别所有病原体类别。为了引起疾病，病原生物必须能够克服物理障碍，抑制或逃避免疫感知，并从宿主组织中获取营养。因此，为了促进其中一些过程，病原体会分泌促进定植的效应蛋白。这篇综述涵盖了效应器生物学领域的最新进展，重点关注来自不同病原体的效应器所针对的保守细胞过程。讨论了效应器促进病原体进入宿主内部、抑制植物免疫感知以及改变宿主生理学以获得病原体益处的能力。病原体还根据感染阶段以空间和时间方式部署效应器。最近的进展也增强了我们对作用于特定植物器官和组织的效应器的理解。效应器是优秀的细胞探针，有助于深入了解生物过程以及植物免疫信号网络中的关键脆弱点。
Plants possess large arsenals of immune receptors capable of recognizing all pathogen classes. To cause disease, pathogenic organisms must be able to overcome physical barriers, suppress or evade immune perception, and derive nutrients from host tissues. Consequently, to facilitate some of these processes, pathogens secrete effector proteins that promote colonization. This review covers recent advances in the field of effector biology, focusing on conserved cellular processes targeted by effectors from diverse pathogens. The ability of effectors to facilitate pathogen entry into the host interior, suppress plant immune perception, and alter host physiology for pathogen benefit is discussed. Pathogens also deploy effectors in a spatial and temporal manner, depending on infection stage. Recent advances have also enhanced our understanding of effectors acting in specific plant organs and tissues. Effectors are excellent cellular probes that facilitate insight into biological processes as well as key points of vulnerability in plant immune signaling networks.