Anal atresia: Effect of smoking and drinking habits during pregnancy
Anal atresia: Effect of smoking and drinking habits during pregnancy
复制标题
DOI：
10.1007/bf01900599
复制
发表时间：
1995-12-01
期刊：
影响因子：
--
通讯作者：
Kuroki, Y
中科院分区：
文献类型：
--
作者：
Yuan, P;Okazaki, I;Kuroki, Y
我们使用基于人口的神奈川出生缺陷监测计划（KAMP）的216，707例出生婴儿的数据，进行了一项病例对照研究，以评估1989-1994年母亲在怀孕期间吸烟和/或饮酒对婴儿肛门闭锁风险的影响。将84例肛门闭锁婴儿的母亲吸烟（包括被动吸烟）和/或母亲在怀孕期间饮酒的频率与174例匹配的对照组进行比较。其中单纯性肛门闭锁49例，综合征性肛门闭锁35例。我们的研究结果表明，母亲在怀孕早期饮酒与孤立性肛门闭锁的风险增加有关（OR=4.8，95%CI 1.2 - 19.1，p
Using data compiled from 216,707 births from the population-based Kanagawa Birth Defects Monitoring Program (KAMP), we conducted a case-control study to evaluate the effect of maternal smoking and/or drinking during pregnancy on the risk of infants' anal atresia in 1989-1994. The frequency of maternal smoking (including passive smoking) and/or maternal drinking during pregnancy among 84 infants with anal atresia was compared with 174 matched controls. The 84 anal atresias include 49 cases of isolated anal atresia and 35 cases of syndromal anal atresia. Our findings suggest that maternal drinking during early pregnancy is associated with an increased risk of isolated anal atresia (OR=4.8, 95% CI 1.2 to 19.1, p