THE BIOLOGICAL BASIS FOR SELF-INJURY IN THE MENTALLY-RETARDED
THE BIOLOGICAL BASIS FOR SELF-INJURY IN THE MENTALLY-RETARDED
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DOI：
10.1016/0270-4684(82)90004-0
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
HARRIS, J
中科院分区：
文献类型：
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作者：
CATALDO, MF;HARRIS, J
自伤行为对行为学和生物医学研究者都提出了临床和学术挑战。生物医学研究的最新进展提出了一些特定的生物学基础的自我伤害。这项研究进行了审查的可能性，一个具体的生物学解释自伤可以先进。正常大脑功能所必需的生化物质缺乏，CNS神经发育不足，发育早期的孤立和疼痛相关经历，改变的神经输入，特别是感觉刺激，对疼痛的神经不敏感，以及身体对疼痛和损伤产生阿片样物质（内源性阿片）的能力，所有这些都导致了自我伤害行为的生物学基础。没有一个单一的解释已经被明确证明是弱智者自残的原因。将行为治疗方法与生物学解释相结合，特别是与疼痛的生物化学相关的解释，可能会为理解和成功消除自我伤害行为提供重要突破的机会。
Self-injurious behavior has presented a clinical and academic challenge to both behavioral and biomedical researchers. Recent advances in biomedical research suggest a number of specific biological bases for self-injury. This research was reviewed with regard to the possibility that a specific biological explanation for self-injury could be advanced. Deficiencies in biochemicals necessary for normal brain functioning, inadequate neurological development of the CNS, isolation and pain related experiences early in development, altered neurological input particularly sensory irritation, neurological insensitivity to pain, and the body''s ability to produce opiate-like substances (endogenous opiates) in response to pain and injury all offer leads to the biological basis of self-injurious behavior. No single explanation has been definitively proven as a cause for self-injury in the retarded. Consideration of behavioral treatment approaches in combination with biological explanations, especially those related to the biochemistry of pain, may provide the opportunity for important breakthroughs in the understanding and successful elimination of self-injurious behavior.