Tissue mechanics.
Tissue mechanics.
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DOI：
10.1243/emed_jour_1978_007_005_02
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发表时间：
1975
影响因子：
3.5
通讯作者：
R. Kenedi;T. Gibson;J. H. Evans;J. Barbenel
中科院分区：
文献类型：
--
作者：
R. Kenedi;T. Gibson;J. H. Evans;J. Barbenel
从工程学的角度来看，人体是一种载荷传递机制。它受制于自我起源和/或环境强加的行动（亚伯拉罕1965，保罗1967）。这些反过来又表现在对组织的作用上，并且组织通过适当变形来承受和传递相应载荷的能力可以在健康和疾病中表征。组织的这种“载荷-变形”关系的知识可以作为诊断、治疗技术发展（例如重建手术）以及监测治疗进展的基础（Jansen 1955，Vlasblom 1967，Finlay 1970）。组织力学在生物学、生物化学、机械和其他方面的文献在其程度上是令人生畏的（见所附参考书目）。尽管如此，列出存在的知识差距和需要完成的工作仍然比确定与所付出的研究努力相称的任何成就要容易得多，并且可以真正声称与人类患者有关。作者相信在实用生物工程，试图在本文中探讨的原因。他们的能力仅限于医疗和机械方面，本文在这些限制范围内提出。然而，即使是这种有限的探索也会揭示出需要
The human body, from an engineering point of view, is a load-transmitting mechanism. It is subjected to self-originated and/or environmentally-imposed actions (Abrahams 1965, Paul 1967). These in turn manifest themselves in actions on tissue, and the tissue’s capability to withstand and transmit the corresponding loads through deforming appropriately can be characterized in health and disease. Knowledge of such ‘load-deformation’ relations of the tissues can serve as a basis for diagnosis, for the development of techniques of therapy (in reconstructive surgery for example) and in general for monitoring treatment progress (Jansen 1955, Vlasblom 1967, Finlay 1970). The literature of tissue mechanics in its biological, biochemical, mechanical and other aspects is intimidating in its extent (see appended Bibliography). Despite this it is still far easier to list knowledge gaps which exist and work that requires to be done than to identify any achievement commensurate with the research effort expended and which can truly be claimed as relevant to the human patient. The authors-believers in pragmatic bioengineering-attempt in this paper to explore the reasons for this. Their competence is limited to the medical and mechanical aspects and the paper is presented within such limitations. It will, however, emerge that even such a limited exploration uncovers the need for a