Cardiovascular risk factors in the elderly
Cardiovascular risk factors in the elderly
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DOI：
10.1038/sj.jhh.1000668
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发表时间：
1998-09-01
影响因子：
2.7
通讯作者：
Palatini, P
中科院分区：
文献类型：
--
作者：
Casiglia, E;Palatini, P
尽管在青壮年中已经确定了许多心血管疾病发病和死亡的危险因素，但其在老年人中的患病率和重要性却鲜为人知。老年人的风险状况与年轻受试者不同，但在文献中很难找到老年人心血管疾病危险因素的代表性数据。一些典型的“主要”危险因素，如血压（BP）、总胆固醇或左心室肥厚，对老年人（尤其是极端年龄）的心血管死亡率没有明确的预测作用，而通常标记为“次要”的风险指标（血清尿酸、通气功能或蛋白尿）对这些个体确实具有很强的预测价值。在评估老年人的累积风险时必须考虑到这一点，以避免对血压或胆固醇轻度升高的受试者进行过度治疗。
Although a number of risk factors for cardiovascular morbidity and mortality have been identified in young and middle-aged adults, their prevalence and importance are less known in the elderly. Elderly people have a risk profile different from that of younger subjects, but representative data on risk factors for cardiovascular disease in the elderly are difficult to find in the literature. Some typical 'major' risk factors, like blood pressure (BP), total cholesterol or left ventricular hypertrophy, do not have a clear predictive role for cardiovascular mortality in the elderly, especially in the extreme ages, while risk indicators usually labelled as 'minor' (serum uric acid, ventilatory function or proteinuria), do have a strong predictive value in these individuals. This must be taken into account when evaluating the cumulative risk of the elderly, in order to avoid overtreatment of subjects with mildly elevated BP or cholesterol.