Genetic Typing of Classical Swine Fever Virus Isolates from China
Genetic Typing of Classical Swine Fever Virus Isolates from China
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DOI：
10.1111/j.1865-1682.2012.01346.x
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发表时间：
2013-08-01
影响因子：
4.3
通讯作者：
Liu, X. -T.
中科院分区：
文献类型：
--
作者：
Sun, S. -Q.;Yin, S. -H.;Liu, X. -T.
对来自中国不同地区猪瘟疑似病例的73株经典猪瘟病毒（CSFV） E2基因进行了遗传特征分析，并与参考猪瘟病毒进行了比较。所有具有特征的中国病毒被划分为两大类，再细分为四个亚群。大部分分离株（61.6%）属于2群，并进一步划分为2.1、2.2和2.3亚群。亚群2.1是最大的亚群，含有46.6%的分离株；亚群2.3是最小的亚群，只含有1株分离株（1.4%）。其余38.4%的分离株被归为1组内的1.1亚组。但本研究未发现第3组、第1.2亚组和第1.3亚组病毒。本研究为评估病毒来源和制定国家防控战略提供了有用的流行病学信息。
The E2 genes of 73 classical swine fever virus (CSFV) originated from CSF suspected cases in different regions of China were genetically characterized and compared with reference CSF viruses. All Chinese viruses that characterized were segregated into two major groups and subdivided into four subgroups. Most of isolates (61.6%) belonged to group 2 and were further divided into three subgroups: subgroup 2.1, 2.2 and 2.3. Subgroup 2.1 was the largest subgroup which contained 46.6% of isolates, whiles subgroup 2.3 was the smallest subgroup which contained only one isolate (1.4%). The remaining 38.4% of isolates were classified into subgroup 1.1 within group 1. However, no group 3 and subgroups 1.2 and 1.3 viruses were found in this study. This study has provided epidemiological information useful for assessing the virus origin and establishing a national prevention and control strategy against the disease.