Does switching to a tobacco-free waterpipe product reduce toxicant intake? A crossover study comparing CO, NO, PAH, volatile aldehydes, "tar" and nicotine yields.
Does switching to a tobacco-free waterpipe product reduce toxicant intake? A crossover study comparing CO, NO, PAH, volatile aldehydes, "tar" and nicotine yields.
复制标题
改用无烟水烟产品是否可以减少有毒物质的摄入量？
DOI：
10.1016/j.fct.2012.02.041
复制
发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Eissenberg,Thomas
中科院分区：
文献类型：
--
作者：
Shihadeh,Alan;Salman,Rola;Jaroudi,Ezzat;Saliba,Najat;Sepetdjian,Elizabeth;Blank,MelissaD;Cobb,CarolineO;Eissenberg,Thomas
水管（水烟，narghile，水烟）的使用已成为一个全球性的现象，有许多产品的变化。其中一种变化是将一类产品作为“无烟草”替代品销售给“注重健康的用户”。在这项研究中，有毒的产量从水管吸烟使用传统的烟草为基础的和无烟草制剂进行了比较。使用仿人水烟吸烟机复制31名人类参与者的抽吸序列，这些参与者在受控临床环境中完成了两个双盲随意吸烟阶段：一次使用他们选择的烟草产品，一次使用与口味匹配的无烟草产品。结果指标包括一氧化碳，一氧化氮，挥发性醛，尼古丁，焦油和多环芳烃的产量。两种水管制剂产生的烟雾都含有大量的有毒物质。尼古丁产量是制剂之间唯一显著不同的结果。这些发现与广告信息相矛盾，即“草药”水烟产品是烟草产品的健康替代品。
Waterpipe (hookah, narghile, shisha) use has become a global phenomenon, with numerous product variations. One variation is a class of products marketed as “tobacco-free” alternatives for the “health conscious user”. In this study toxicant yields from waterpipes smoked using conventional tobacco-based and tobacco-free preparations were compared. A human-mimic waterpipe smoking machine was used to replicate the puffing sequences of 31 human participants who completed two double-blind ad libitum smoking sessions in a controlled clinical setting: once with a tobacco-based product of their choosing and once with a flavor-matched tobacco-free product. Outcome measures included yields of carbon monoxide, nitric oxide, volatile aldehydes, nicotine, tar, and polycyclic aromatic hydrocarbons. Smoke from both waterpipe preparations contained substantial quantities of toxicants. Nicotine yield was the only outcome that differed significantly between preparations. These findings contradict advertising messages that “herbal” waterpipe products are a healthy alternative to tobacco products.