Expression of glial fibrillary acidic protein by Muller cells in rd chick retina.

Expression of glial fibrillary acidic protein by Muller cells in rd chick retina.
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Muller 细胞在小鸡视网膜中表达神经胶质原纤维酸性蛋白。

DOI:
10.1002/cne.903050405
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发表时间:
1991
期刊:
The Journal of comparative neurology
影响因子:
--
通讯作者:
Semple-Rowland,SL
Semple-Rowland,SL
中科院分区:
--
文献类型:
--
作者:
Semple-Rowland,SL

文献摘要

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Accumulation of glial fibrillary acidic protein (GFAP) in Müller cells has been observed in retinas of several mammalian species secondary to genetically induced degeneration and neuronal injury. In the present series of experiments, I have examined the effects of the rd (retinal degeneration) mutation on the expression of GFAP in retinas of chicks homozygous for the mutation (rd/rd) prior to and following the onset of photoreceptor degeneration, which first appears approximately 7 days posthatch (7dph). Carrier (+/rd) and wild-type (+/+) retinas served as controls.