Natural products: Perspectives in the pharmacological treatment of gastrointestinal anisakiasis
Natural products: Perspectives in the pharmacological treatment of gastrointestinal anisakiasis
复制标题
DOI：
10.1016/j.apjtm.2015.07.017
复制
发表时间：
2015-08-01
影响因子：
3.1
通讯作者：
Navarro, M. C.
中科院分区：
文献类型：
--
作者：
Valero, A.;Romero, M. C.;Navarro, M. C.
目的：评价不同天然产物对异尖线虫L3级幼虫的杀灭活性。方法：通过文献检索、Pubmed、Scope us、Medline、Web of Science和Science Direct等检索工具，从科学期刊、书籍、论文和报道中获取天然产物对单纯异尖线虫L3幼虫活性的调查资料。检索词包括：天然产物、药用植物、精油、萜类衍生物、异尖杉属、抗结节活性。结果：在查阅的文献中，大量文献涉及各种天然产物(植物提取物、精油及其主要成分)的体内外抗异尖线虫活性。结果分析表明，在体外试验中，互花蛇舌草精油和从姜黄中分离出的姜黄酮均为有效成分。表现出了最大的活力。在体内，最活跃的化合物是紫苏醛，紫苏精油的主要成分。结论：本研究表明部分天然产物具有良好的抗异尖线虫活性。
Objective: To evaluate the activity of different natural products against L3 larvae of,Anisakis type I. Methods: Information on investigations into the activity of natural products against the L3 larvae of Anisakis simplex was collected from scientific journals, books, theses and reports via a library and electronic search (using Pubmed, Scopus, Medline, Web of Science and ScienceDirect). The search terms included: natural products, medicinal plants, essential oils, terpenic derivatives, Anisakis, antinematodal activity. Results: In the literature reviewed numerous papers were found concerning the in vitro and in vivo activity against Anisakis type I of various natural products (plant extracts, essential oils and their major components). Analysis of the results showed that in vitro tests the lielalenca alternifolia essential oil and the ar-turmerone isolated from Curcuma ion go. displayed the greatest activity. In vivo, the most active compound was perillaldehyde, the main component of Perilla frutescens essential oil. Conclusions: This study shows that some natural products exhibited promising antianisakis properties.