Regenerative Applications Using Tooth Derived Stem Cells in Other Than Tooth Regeneration: A Literature Review.
Regenerative Applications Using Tooth Derived Stem Cells in Other Than Tooth Regeneration: A Literature Review.
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DOI：
10.1155/2016/9305986
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发表时间：
2016
影响因子：
4.3
通讯作者：
Park YS
中科院分区：
文献类型：
--
作者：
Park YJ;Cha S;Park YS
牙齿来源的干细胞或牙齿干细胞根据它们被分离的位置进行分类，并且代表再生医学的有希望的细胞来源。最初，作为间充质干细胞的一种，它们被认为是骨髓基质细胞的替代物。它们有许多共同点，但也有一些不同之处。考虑到它们在发育和牙齿结构的稳态中的原始功能，这些细胞在牙科中的许多应用都针对牙齿结构再生;然而，已经广泛尝试了在牙齿结构之外的应用。从丢弃或移除的牙齿中获得的可用性可以是作为自体细胞来源的先天益处。它们起源于神经嵴，导致神经学和许多其他应用的开发。本文简要介绍了牙源性干细胞在牙齿再生以外领域的再生应用的现状和前景。
Tooth derived stem cells or dental stem cells are categorized according to the location from which they are isolated and represent a promising source of cells for regenerative medicine. Originally, as one kind of mesenchymal stem cells, they are considered an alternative of bone marrow stromal cells. They share many commonalties but maintain differences. Considering their original function in development and the homeostasis of tooth structures, many applications of these cells in dentistry have aimed at tooth structure regeneration; however, the application in other than tooth structures has been attempted extensively. The availability from discarded or removed teeth can be an innate benefit as a source of autologous cells. Their origin from the neural crest results in exploitation of neurological and numerous other applications. This review briefly highlights current and future perspectives of the regenerative applications of tooth derived stem cells in areas beyond tooth regeneration.