The Impact of Menopausal Symptoms on Quality of Life, Productivity, and Economic Outcomes
The Impact of Menopausal Symptoms on Quality of Life, Productivity, and Economic Outcomes
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DOI：
10.1089/jwh.2012.3719
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发表时间：
2013-11-01
影响因子：
3.5
通讯作者：
Shah, Sonali
中科院分区：
文献类型：
--
作者：
Whiteley, Jennifer;DiBonaventura, Marco daCosta;Shah, Sonali
背景资料：本研究的目的是调查绝经期症状和绝经期症状严重程度对健康相关生活质量（HRQoL）、工作障碍、医疗保健利用和费用的影响。研究方法：使用了2005年美国国家健康和健康调查的数据，分析中仅包括40-64岁无癌症史的女性（N= 8，811）。使用回归模型（并控制人口统计学和健康特征差异），将报告出现绝经期症状的女性（n = 4，116）与未出现绝经期症状的女性（n = 4，695）在HRQoL、工作障碍和医疗保健利用方面进行比较。此外，个体绝经期症状在一组单独的回归模型中被用作结果的预测因子。结果：分析中女性的平均年龄为49.8岁（标准差为5.9）。经历更年期症状的妇女报告的HRQoL水平显着较低，显着较高的工作障碍，和医疗保健利用比妇女没有更年期症状。抑郁、焦虑和关节僵硬是与健康结果相关性最强的症状。结论：月经症状可能是中年妇女的一个重大的人文和经济负担。
Background: The aim of this study was to investigate the impact of menopausal symptoms and menopausal symptom severity on health-related quality of life (HRQoL), work impairment, healthcare utilization, and costs. Methods: Data from the 2005 United States National Health and Wellness Survey were used, with only women 40-64 years without a history of cancer included in the analyses (N=8,811). Women who reported experiencing menopausal symptoms (n=4,116) were compared with women not experiencing menopausal symptoms (n=4,695) on HRQoL, work impairment, and healthcare utilization using regression modeling (and controlling for demographics and health characteristic differences). Additionally, individual menopausal symptoms were used as predictors of outcomes in a separate set of regression models. Results: The mean age of women in the analysis was 49.8 years (standard deviation,5.9). Women experiencing menopausal symptoms reported significantly lower levels of HRQoL and significantly higher work impairment, and healthcare utilization than women without menopausal symptoms. Depression, anxiety, and joint stiffness were symptoms with the strongest associations with health outcomes. Conclusions: Menopausal symptoms can be a significant humanistic and economic burden on women in middle age.