Changes in brain activation associated with use of a memory strategy: a functional MRI study
Changes in brain activation associated with use of a memory strategy: a functional MRI study
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DOI：
10.1016/j.neuroimage.2004.10.033
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发表时间：
2005-02-15
期刊：
影响因子：
5.7
通讯作者：
Fujii, T
中科院分区：
文献类型：
--
作者：
Kondo, Y;Suzuki, M;Fujii, T
已有研究证实，记忆策略可以显著提高记忆回忆的绩效。然而，还没有直接的研究来检验与个体内定位方法的使用相关的大脑活动的变化。在本研究中，我们使用功能磁共振成像技术，在编码和回忆两个阶段，用轨迹法比较了教学前后的脑激活。由此产生的行为数据显示，使用LOCAL方法显著提高了记忆回忆的分数。影像资料显示，与指令前编码相比，指令指令后编码与右侧额下回、双侧额中回、左侧梭形回和双侧舌回/扣带后回的信号增加有关。与指令前比较，指令后记忆在左侧海马旁回/脾后皮质/扣带回/舌回、左侧楔前回、左侧梭形回、右侧舌回/扣带回均有显著激活。本研究证实了与使用基因座方法相关的脑激活模式的变化：左侧梭形和舌头活动与编码和回忆阶段有关，双侧额叶前部活动与编码阶段有关，双侧额叶前额叶活动与编码阶段有关，双侧前额叶活动与回忆阶段有关，而海马旁回后部、脾后皮质和楔前脑区的活动与回忆阶段有关。这些发现表明，调节情景编码和提取的大脑网络因个体如何编码相同的刺激而有所不同。(C)2004 Elsevier Inc.保留所有权利。
It has been confirmed that some kinds of what are called memory strategies dramatically improve the performance of memory recall. However, there has been no direct research to examine changes in brain activity associated with the use of the method of loci within individuals. In the present study, using fMRI, we compared brain activations before and after instruction in the method of loci during both the encoding and recall phases. The resulting behavioral data showed that the use of the method of loci significantly increased scores for memory recall. The imaging data showed that encoding after instruction in the method of loci, relative to encoding before it, was associated with signal increases in the right inferior frontal gyros, bilateral middle frontal gyros, left fusiform gyros, and bilateral lingual gyrus/posterior cingulate gyrus. Comparison of recall after instruction in the method of loci with that before it showed significant activation in the left parahippocampal gyrus/retrosplenial cortex/cingulate gyrus/lingual gyros, left precuneus, left fusiform gyros, and right lingual gyrus/cingulate gyrus. The Present study demonstrated the changes in brain activation pattern associated with the use of the method of loci; left fusiform and lingual activity was associated with both the encoding and recall phases, bilateral prefrontal activity with the encoding phase, and activity of the posterior part of the parahippocampal gyros, retrosplenial cortex, and precuneus with the recall phase. These findings suggest that brain networks mediating episodic encoding and retrieval vary with how individuals encode the same stimuli. (C) 2004 Elsevier Inc. All rights reserved.