Early fusion of two human embryos?
Early fusion of two human embryos?
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两个人类胚胎的早期融合？
作者：
A. Chapelle;J. Schröder;P. Rantanen;Björn Thomasson;M. Niemi;A. Tiilikainen;R. Sanger;E. Robson
本文描述了一种具有XX和XY细胞系的婴儿嵌合体。她右侧的卵巢大体和组织结构正常，左侧有卵巢。根据未培养细胞的荧光Y小体发现以及长期培养的有丝分裂的核型判断，性腺活检发现1-15%的XY细胞。卵巢和睾丸结构在两种细胞系中的频率相似。在组织培养过程中没有细胞体外选择的证据。
An infant chimaera with an XX and an XY cell line is described. She had a macroscopically and histologically normal ovary on the right and an ovotestis on the left. Biopsies from the gonads revealed 1–15% of XY cells as judged by fluorescent Y body findings of uncultured cells as well as by karyotypes of mitoses from long term cultures. Ovarian and testicular structures had similar frequencies of the two cell lines. There was no evidence of in vitro selection of cells during tissue culture.