The macula densa: recent developments.
The macula densa: recent developments.
复制标题
致密黄斑：最新进展。
DOI：
10.1097/00004872-199607000-00003
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发表时间：
1996
影响因子：
4.9
通讯作者：
Harris,RC
中科院分区：
文献类型：
--
作者：
Harris,RC
致密黄斑的形态在肾小球、Henle环粗大升支的致密斑区、肾小球外系膜(由Goormaghtigh细胞组成)和传入小动脉的肾小球旁细胞之间有密切而不变的解剖关系，它们共同构成肾小球旁结构[4](图1)。1937年，Goormaghtigh[5]注意到致密斑细胞靠近传入和传出小动脉，并首次提出这一肾单位段与肾小球功能之间的功能关系。1964年，Vander和Moller[6]确定致密黄斑的肾素释放受肾小管液成分的调节。图劳和施纳曼[7]在1965年首次
Morphology of the macula densa There is a close and unvarying anatomic relationship between the glomerulus, the macula densa region of the thick ascending limb of the loop of Henle, the extraglomerular mesangium (which consists of Goormaghtigh cells), and the juxtaglomerular cells of the afferent arteriole; together they form the juxtaglomerular apparatus [4](Fig. 1). Goormaghtigh [5] noted the proximity of macula densa cells to afferent and efferent arterioles in 1937, and was the first to propose a functional relationship between this nephron segment and glomerular function. Vander and Moller [6] in 1964 determined that renin release was regulated by the tubular fluid composition of the macula densa. Thurau and Schnermann [7] in 1965 first