Recent developments of chemical imaging sensor systems based on the principle of the light-addressable potentiometric sensor

Recent developments of chemical imaging sensor systems based on the principle of the light-addressable potentiometric sensor
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DOI:
10.1016/j.snb.2014.09.002
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发表时间:
2015-02-01
影响因子:
8.4
通讯作者:
Schoening, Michael J.
Schoening, Michael J.
中科院分区:
化学1区
文献类型:
--
作者:
Yoshinobu, Tatsuo;Miyamoto, Ko-ichiro;Schoening, Michael J.

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光可寻址电位传感器(LAPS)是一种具有场效应结构的电化学传感器,用于检测传感器表面能斯特电位的变化,被测区域由光照定义。由于这种光寻址能力,LAPS可以应用于化学成像传感器系统,它可以可视化特定目标离子在传感器表面的二维分布。化学成像传感器系统有望用于分析各种电化学和生物样品中的反应和扩散。综述和讨论了基于LAPS的化学成像传感器系统在空间分辨率、测量速度、成像质量、小型化以及与微流控器件集成等方面的最新进展。(C)2014爱思唯尔B.V.保留所有权利。
The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor with a field-effect structure to detect the variation of the Nernst potential at its sensor surface, the measured area on which is defined by illumination. Thanks to this light-addressability, the LAPS can be applied to chemical imaging sensor systems, which can visualize the two-dimensional distribution of a particular target ion on the sensor surface. Chemical imaging sensor systems are expected to be useful for analysis of reaction and diffusion in various electrochemical and biological samples. Recent developments of LAPS-based chemical imaging sensor systems, in terms of the spatial resolution, measurement speed, image quality, miniaturization and integration with microfluidic devices, are summarized and discussed. (C) 2014 Elsevier B.V. All rights reserved.