Dissociable roles of prefrontal and anterior cingulate cortices in deception
Dissociable roles of prefrontal and anterior cingulate cortices in deception
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DOI：
10.1093/cercor/bhi097
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发表时间：
2006-02-01
期刊：
影响因子：
3.7
通讯作者：
Fujii, T
中科院分区：
文献类型：
--
作者：
Abe, N;Suzuki, M;Fujii, T
最近的神经影像学研究表明，前额叶和前扣带皮层在欺骗中的重要性。然而，很少有人知道这些区域中的每一个在欺骗中的作用。使用正电子发射断层扫描（PET），我们测量了参与者对两种类型的现实世界事件（有经验和无经验）说出真相或谎言时的大脑激活。成像数据显示，背外侧、腹外侧和内侧前额叶皮质的活动通常与两种类型的欺骗（假装知道和假装不知道）有关，而前扣带皮层（ACC）的活动只与假装不知道有关。只有在假装不知道的情况下，前扣带回的局部脑血流量（rCBF）增加与背外侧前额叶皮层的正相关。这些结果表明，外侧和内侧前额叶皮质在欺骗中起着普遍的作用，而前扣带皮层则专门负责假装不知道。
Recent neuroimaging studies have shown the importance of the prefrontal and anterior cingulate cortices in deception. However, little is known about the role of each of these regions during deception. Using positron emission tomography (PET), we measured brain activation while participants told truths or lies about two types of real-world events: experienced and unexperienced. The imaging data revealed that activity of the dorsolateral, ventrolateral and medial prefrontal cortices was commonly associated with both types of deception (pretending to know and pretending not to know), whereas activity of the anterior cingulate cortex (ACC) was only associated with pretending not to know. Regional cerebral blood flow (rCBF) increase in the ACC was positively correlated with that in the dorsolateral prefrontal cortex only during pretending not to know. These results suggest that the lateral and medial prefrontal cortices have general roles in deception, whereas the ACC contributes specifically to pretending not to know.