INTRINSIC CONTRACTILITY OF PRE-NODAL LYMPH VESSELS AND LYMPH-FLOW IN HUMAN LEG
INTRINSIC CONTRACTILITY OF PRE-NODAL LYMPH VESSELS AND LYMPH-FLOW IN HUMAN LEG
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DOI：
10.1152/ajpheart.1980.239.6.h775
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发表时间：
1980-01-01
影响因子：
--
通讯作者：
ENGESET, A
中科院分区：
文献类型：
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作者：
OLSZEWSKI, WL;ENGESET, A
为研究人下肢淋巴管的固有收缩对淋巴液的推进作用，测定了下肢皮下淋巴管的末端压力、侧压力和淋巴液流量。淋巴管在25名正常男子在水平和直立的位置，在休息期间和收缩的脚和小腿肌肉。由血管的内在收缩产生的扁桃体淋巴结末端压力范围在12和70 mmHg之间，但在某些情况下达到100 mmHg以上的值。有淋巴液自由流动时，侧压较低，在5 ~ 30 mmHg之间（P < 0.01）。淋巴压几乎没有流体静力学成分。水平位和直立位时，足肌和小腿肌肉的收缩对收缩末期压力无显著影响，但侧压力略有增加（P < 0.01）。脉搏波频率无明显增加（P < 0.01）。脉冲幅度没有变化。淋巴流发生在休息的人的肢体和肢体肌肉收缩期间，只有在淋巴脉冲波。在两波之间的时间里没有流动。肌肉收缩期平均淋巴流量高于静息期（P < 0.01）。足部的外部按摩没有产生任何淋巴压升高。脉搏波频率和淋巴流量增加。通过外部按摩或注射液体使淋巴管充满引起内在收缩。诱发收缩的压力阈值在不同的受试者中从5到25 mmHg不等。人体腿部淋巴收集器的内在收缩是肢体其余部分淋巴流动的主要因素。
To study the efficiency of intrinsic contractions of lymphatics in propelling lymph in human legs, the end and lateral pressures and lymph flow were measured in leg s.c. lymph vessels in 25 normal men in a horizontal and upright position, during rest and during contractions of the foot and calf muscles. Systolic lymph end pressures generated by intrinsic contractions of lymphatics ranged between 12 and 70 mmHg, but in some cases reached values above 100 mmHg. Systolic lymph lateral pressures with free lymph flow were lower and ranged between 5 and 30 mmHg (P < 0.01). There was almost no hydrostatic component of lymph pressure. Contractions of foot and calf muscles in the horizontal and upright position did not significantly effect systolic end pressures, but slightly increased lateral pressures (P < 0.01). There was no increase in the frequency of pulse waves (P < 0.01). Pulse amplitudes did not change. Lymph flow occurred in the resting human limbs and during limb muscle contractions only during the lymphatic pulse waves. There was no flow in the periods between the waves. The mean lymph flow was higher during muscular contractions than during the resting period (P < 0.01). External massaging of the foot did not produce any rise in lymph pressure. The frequency of pulse waves and lymph flow increased. Filling of the lymphatics with lymph by external massaging or injection of fluid evoked intrinsic contractions. The pressure threshold for evoking contractions varied in different subjects from 5 to 25 mmHg. Intrinsic contractions of lymphatic collectors in the human leg is the main factor responsible for lymph flow during the rest of the extremity.