Comparison of Blood Loss between Neutral Drainage with Tranexamic Acid and Negative Pressure Drainage without Tranexamic Acid Following Primary Total Knee Arthroplasty
Comparison of Blood Loss between Neutral Drainage with Tranexamic Acid and Negative Pressure Drainage without Tranexamic Acid Following Primary Total Knee Arthroplasty
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初次全膝关节置换术后使用氨甲环酸中性引流与不使用氨甲环酸负压引流的失血量比较
DOI：
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发表时间：
2016
影响因子：
3.1
通讯作者：
Sung Jung
中科院分区：
文献类型：
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作者：
Dong hwi Kim;G. Lee;Sang Hong Lee;C. Pak;S. H. Park;Sung Jung
目的减少全膝关节置换术(TKA)大出血的方法有很多。在我们的研究中，使用氨甲环酸和中性引流来减少总出血量。材料与方法研究对象为2012年3月至2013年1月收治的97例TKA患者。研究组给予氨甲环酸加中性引流。研究组分为I组(单侧，n=29)和III组(双侧，n=17)。对照组为II组(单侧，n=35)和IV组(双侧，n=16)。结果I组术后第1、2天引流量及总引流量均减少，差异有统计学意义(p<；0.05)。III组和IV组之间，III组的引流量较小。III组术后第1天引流量和总引流量均显著减少(p<；0.05)。在I组和II组之间，总失血量无统计学意义，而在III组和IV组之间，该值有显著差异。结论双侧TKA术后静脉注射氨甲环酸，中性引流3h，有助于减少术中总出血量，值得推广。
Purpose There are many methods to reduce massive bleeding during total knee arthroplasty (TKA). In our study, tranexamic acid and neutral drainage were used to decrease total blood loss. Materials and Methods The study was performed on 97 TKA patients from March 2012 to January 2013. In the study group, tranexamic acid was administered and neutral drainage was applied. The study group had group I (unilateral, n=29) and group III (bilateral, n=17). The control group had group II (unilateral, n=35) and group IV (bilateral, n=16). Results In group I, the drainage volume on the 1st and 2nd postoperative days and the total drainage decreased with statistical significance (p<0.05). Between group III and group IV, group III had less drainage volume. In group III, the drainage volume on the 1st postoperative day and total drainage volume decreased statistically significantly (p<0.05). Between groups I and II, total blood loss showed no statistically significant difference, whereas between groups III and IV, the value was significantly different. Conclusions Intravenous administration of tranexamic acid with neutral drainage for 3 postoperative hours is a recommendable method because it can be helpful in reducing total blood loss in bilateral TKA.
全膝关节和全髋关节置换手术中的红细胞输注。
影响因子：
2.9
作者：
Surgenor,DM;Wallace,EL;Churchill,WH;Hao,SH;Chapman,RH;Poss,R
通讯作者：
Poss,R