Slow Theta tACS of the Right Parietal Cortex Enhances Contralateral Visual Working Memory Capacity
Slow Theta tACS of the Right Parietal Cortex Enhances Contralateral Visual Working Memory Capacity
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DOI：
10.1007/s10548-019-00702-2
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发表时间：
2019-05-01
期刊：
影响因子：
2.7
通讯作者：
Sauseng, Paul
中科院分区：
文献类型：
--
作者：
Bender, Monika;Romei, Vincenzo;Sauseng, Paul
最近的研究表明，通过经颅交流电流刺激（tACS）调节顶叶θ波频率可以改变视觉工作记忆容量。然而，这种效应是否部分是由前额叶皮层和皮层下结构的共同刺激引起的，尚不清楚。据推测，在没有额外的前额叶或皮层下刺激的情况下，顶叶的局灶性tACS会导致与文献报道相似的效果。健康的年轻参与者在接受4Hz、7Hz或假性刺激的局灶顶叶tac时接受视觉工作记忆范式测试。焦点右后侧4Hz的tACS只导致对侧视觉半球工作记忆容量的增加。4Hz tACS对后皮层的单独刺激重复了最近文献报道的效果，证实了刺激前额皮质或皮层下结构不是这些观察结果的主要驱动因素。
Recent research suggests alteration of visual working memory capacity by modulation of parietal theta frequency via transcranial alternating current stimulation (tACS). However, it remains to be clarified whether this effect is partly driven by co-stimulation of prefrontal cortex and subcortical structures. It was hypothesized that focal tACS over the parietal lobe without additional prefrontal or subcortical stimulation should lead to similar effects as reported in the literature. Healthy, young participants were tested on a visual working memory paradigm while receiving either focal parietal tACS at 4Hz, at 7Hz or sham stimulation. Focal right posterior 4Hz tACS led to increased working memory capacity strictly for the visual hemifield contralateral to stimulation. Exclusive stimulation of posterior cortex by 4Hz tACS replicates effects recently reported in literature, confirming that stimulation of the prefrontal cortex or subcortical structures are not a primary driver of these observations.